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Recruiting studies


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ISRCTNAcronym & TitleStatusTypeOpen to additional sites
 Adherence to Prophylaxis among Young Haemophilia Patients - Adherence to Prophylactic Treatment among Adolescents and Young Adults with HaemophiliaOpenObservationalYes, within lead country only
 Asthma and Nocturnal Hypoxia in Sickle Cell Anemia (SAC) II - Asthma and Nocturnal Hypoxia in Sickle Cell Anemia (SAC) IIOpenObservationalNo
 BRIDGE-BPD - Genetic analysis of inherited platelet conditionsOpenObservationalYes, within lead country only
 CCRN 471 (Haemophilia) - An open-label, multi-centre, un-controlled trial to assess efficacy and safety of NNC-0156-0000-0009 during surgical procedures in patients with haemophilia BOpenInterventionalNo
 CCRN 472 (Haemophilia) - Safety and efficacy of NNC-0156-0000-0009 after long-term exposure in patients with haemophilia BOpenInterventionalNo
 CCRN 542 (anaemia/ulcerative colitis) - A prospective, multicentre, randomized, double-blind, placebo controlled study with oral ST10-021 for the treatment of iron deficiency anaemia in subjects with quiescent ulcerative colitis where oral ferrous preparations have failed or cannot be used (AEGIS 1)OpenInterventionalNo
 CCRN 618 (Crohns Disease) - A Prospective, Multicentre, Randomised, Double-Blind, Placebo Controlled Study With Oral ST10-021 For The Treatment Of Iron Deficiency Anaemia In Subjects With Quiescent Crohn’s Disease Where Oral Ferrous Preparations Have Failed Or Cannot Be UsedOpenInterventionalNo
 CCRN 680 (Hemophilia A) - Phase II/III partial randomized, open label trial using BAY 94-9027 for the prophylaxis and treatment of bleeding in severe Hemophilia A.OpenInterventionalNo
 CCRN 756 (Haemophilia A) - A Multi-national Trial Evaluating Safety and Efficacy, including Pharmacokinetics, of NNC 0129-0000-1003 when Administered for Treatment and Prophylaxis of Bleeding in Patients with Haemophilia AOpenInterventionalNo
 CCRN 757 (Haemophilia A) - EFFICACY AND SAFETY OF N8-GP DURING SURGICAL PROCEDURES IN PATIENTS WITH HAEMOPHILIA AOpenInterventionalNo
 CCRN 767 (Hemophilia A) - An Open-Label, Multicenter Evaluation of the Long-Term Safety and Efficacy of Recombinant Human Coagulation Factor VIII Fusion Protein (rFVIIIFc) in the Prevention and Treatment of Bleeding Episodes in Previously Treated Subjects With Hemophilia AOpenInterventionalNo
 CCRN 991 (Hep B_liver transplant) - In open, prospective, single arm study investigating efficacy and safety of human hepatitis B immunoglobulin Zutectra in liver transplanted patients - the ZEUS Study.OpenInterventionalNo
 Determinants of Severity in HbSC Disease - Determinants of Severity in HbSC DiseaseOpenObservationalNo
 DRN794 - Clinical Evaluation Of LifeScan Production And Development Diabetes Monitoring SystemsOpenInterventional and ObservationalNo
73819751ExACT Extended anticoagulation treatment for VTE: a randomised trial - A randomised controlled trial of extended warfarin treatment versus routine warfarin treatment for the prevention of recurrent venous thromboembolism and post thrombotic syndrome in patients being treated for a first episode of unprovoked VTEOpenInterventional-unknown-
 FIX Study - Evaluation of Assay Methodology to Optimise Clinical Management of Factor IX Replacement Therapy in Haemophilia BOpenObservationalNo
 Free Light Chains in Emergency Care - A study to investigate the role of combined serum free lights chains (cFLCS), the modified emergency warning score (MEWS) and the early warning score (EWS) in emergency care.OpenObservationalNo
77951167Genotyping and platelet phenotyping (GAPP) - Mild bleeding disorders caused by platelet defectsOpenObservationalYes, within lead country only
 GRAPHICS - Genetic Regulators and Platelets in Cardiac SurgeryOpenObservationalNo
23537803HA-1 Heterologous Prime Boost Vaccine Study - A phase I clinical trial of the vaccination of healthy human volunteers against the minor histocompatibility antigen (mHAg) HA-1 using a DNA and MVA 'prime/boost' regimenOpenInterventionalNo
 Haemophilia: Investigating Physical Performance Outcomes (HIPPO) - An observational study in people with Haemophilia Investigating Physical Performance Outcomes (HIPPO)OpenObservationalYes, within lead country only
23996532HLA Epitope-Matched Platelet Transfusion Study - A comparison of HLA epitope-matched with standard HLA-matched platelet transfusions in raising the platelet count increment in alloimmunised thrombocytopenic patients with aplastic anaemia or low risk myelodysplastic syndrome: A double-blind randomised crossover superiority trial.OpenInterventionalYes, within lead country only
05026912InCiTE - Intracranial haemorrhage in thrombocytopenic haematology patients - Intracranial Haemorrhage in Thrombocytopenic Haematology Patients. A case control StudyOpenObservationalYes, within and outside lead country
 Intelligent Stem Cell Culture Systems - Intelligent Stem Cell Culture SystemsOpenObservationalNo
76424792IVANOF1 Study - The Effect of Intravenous Iron on Postoperative Transfusion Requirements in Hip Fracture Patients – A Pilot StudyOpenInterventionalNo
 Molecular Investigation of Haematopoietic Malignancy - The investigation of molecular biological alterations in haematological malignancyOpenObservationalYes, within lead country only
 Peripheral blood leukocytes in health and disease - Characterisation of peripheral blood leukocytes in health and diseaseOpenObservationalNo
56366401PROmPT Platelet Responsiveness and Outcome from Platelet Transfusion - PROmPT Platelet Responsiveness and Outcome from Platelet Transfusion Does inherent variation in donor platelet function affect the clinical efficacy of apheresis platelets? A randomised double blind single centre trialOpenInterventionalNo
79841657Reversal of over-anticoagulation with vitamin K - Reversal of over-anticoagulation using a ‘tailored’ vitamin K dosing regimen: towards a better management of anticoagulation therapyOpenInterventionalNo
 Study of haematology in newborns with Down syndrome - Study of haematology in newborns with Down syndrome and follow-up. (Oxford-Imperial Down syndrome haematology cohort study)OpenObservationalYes, within and outside lead country
 The Genetic Basis of Dsykeratosis Congenita and Aplastic Anaemia - The Genetic Basis of Dsykeratosis Congenita and Aplastic Anaemia -OpenObservationalNo
 The Genetic Control and Predictive Value of HbF in Sickle Cell Disease - A Multi-centre, Genotype-phenotype Study to Investigate the Genetic Control and Predictive Value of Foetal Haemoglobin and F-cell Levels in Sickle Cell DiseaseOpenObservationalYes, within lead country only
 Trauma Coagulopathy and Massive Transfusion - Activation of Coagulation and Inflammation in Trauma IIOpenObservationalYes, within lead country only
 UK TTP Registry - United Kingdom Thrombotic Thrombocytopenic Purpura Registry: A prospective study of Thrombotic Thrombocytopenic Purpura in the UKOpenObservationalYes, within and outside lead country
 UKAITPR - United Kingdom Adult Idiopathic Thrombocytopenic Purpura (ITP) Registry: An Investigation of Disease Progression, Treatment Effectiveness, and Co-morbid ConditionsOpenObservationalYes, within and outside lead country




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