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| | Accuracy and Diagnostic Impact of Radiographer Chest X-ray Reporting - Establishing the Diagnostic Accuracy of Radiographer Chest X-ray Reports and Their Influence on Clinicians' Clinical Reasoning: A Comparison with Consultant Radiologists | In Set-Up Pending NHS Permission | Observational | No |
| | An Auditory Battery to Predict Functional Outcome in Coma - An Auditory Battery to Predict Functional Outcome in Patients with Reduced Conscious Level Coma | In Set-Up NHS Permission Received | Observational | No |
| | Assessing and Improving the Quality of CPR using feedback device - Assessing and Improving the Quality of Cardiopulmonary Resuscitation (CPR) delivered during Pediatric cardiac arrest using a novel Pediatric CPR feedback device | In Set-Up NHS Permission Received | Interventional | No |
| | Automated Software Grading of Diabetic Retinopathy - Can automated diabetic retinopathy image assessment software replace one or more steps of manual imaging grading and is this cost-effective for the English National Screening Programme? | In Set-Up Pending NHS Permission | Observational | No |
| | Brain Imaging in Babies (BIBS) - Brain Imaging and Infant Development Study | In Set-Up Pending NHS Permission | Observational | No |
| | Cardiopulmonary Resuscitation Debriefing study (CODE study) - A Study of the Use of Debriefing to Improve Cardiopulmonary Resuscitation Delivery at In-hospital Adult Cardiac Arrest | In Set-Up Pending NHS Permission | Interventional | No |
| | CHILD Study - The Cambridge Human Imaging and Longitudinal Development (CHILD) Study: Prenatal, neonatal and postnatal hormonal effects on infant health and brain development | In Set-Up Pending NHS Permission | Observational | Yes, within lead country only |
| | CRP-VLDL in Sepsis - The Clinical, Diagnostic and Treatment Relevance of Complexes between C-reactive Protein and Very Low Density Lipoprotein in Patients with Sepsis | In Set-Up NHS Permission Received | Observational | No |
| | Defining the Genetics and Molecular Biology of Cystinuria - Pilot study to understand cystinuria disease in children and adults in the Southwest and West Midlands areas by recording clinical data, genotyping them and immortalising kidney cells from their urine. | In Set-Up NHS Permission Received | Observational | Yes, within lead country only |
| | Developing New Tests for Assessing Children with Retinal Dystrophies - Developing new tests of visual acuity, contrast sensitivity and the visual field using remote eye tracking for use with infants and children in a clinical setting | In Set-Up Pending NHS Permission | Observational | No |
| 65108429 | DINOSAUR Study - Duration of INtravenous antibiOtic therapy for Septic Arthritis or acUte osteomyelitis in a paediatRic population (DINOSAUR) | In Set-Up Pending NHS Permission | Observational | Yes, within and outside lead country |
| | Diprenorphine PET PLP DBS - Deep brain stimulation for phantom limb pain: Does stimulation of the peri-ventricular grey produce an opioid-mediated analgesia – A pilot PET imaging study | In Set-Up Pending NHS Permission | Observational | No |
| | Easy and accurate manual blood pressure measurement - Novel engineering solutions for easy and accurate manual blood pressure measurement | In Set-Up NHS Permission Received | Observational | No |
| | Empathy, Frail Older People and the Hospital Discharge Process - Fear and Loathing in the Acute Hospital? The Recognition and Maintenance of Empathy during the Discharge Process towards Frail Older People | In Set-Up Pending NHS Permission | Observational | No |
| | EMTICS - European Multicentre Tics in Children Study | In Set-Up Pending NHS Permission | Observational | No |
| | ETPOS - ETPOS: European Transfusion Practice and Outcome Survey. An observational outcome study of transfusion practice in surgical patients (excluding cardiothoracic surgery) throughout Europe. | In Set-Up NHS Permission Received | Observational | No |
| 69055668 | Evaluation of Cytology and HPV Testing for Anal Pre-cancer - Evaluation of cytology and HPV testing for testing for anal intraepithelial neoplasia in high-risk populations in the UK | In Set-Up Pending NHS Permission | Interventional | No |
| | Evaluation of the Efficacy of a Mobile Transcranial Direct Current Device in Chronic Pain - Evaluation of the Efficacy of a Mobile Transcranial Direct Current Device in Chronic Pain Patients who have Previously Responded to Rapid Transcranial Magnetic Stimulation. | In Set-Up Pending NHS Permission | Interventional | No |
| | Exercise, Cognition and Brain Vitality - Exercise, Cognition and Brain Vitality | In Set-Up NHS Permission Received | Observational | No |
| | Exploring Stakeholders Information Needs on Medicines Development - Qualitative Study Exploring Patients' and the Public's Information Needs and Key Stakeholders Perspectives on the Medicines Development Process | In Set-Up Pending NHS Permission | Observational | No |
| | Exploring the Critical Review Capacity of CCGs - Improving the Absorptive Capacity of Clinical Commissioning Groups (CCGs) for Critical Review of Evidence to Reduce Unplanned Elderly Care Admissions into Acute Hospitals | In Set-Up NHS Permission Received | Observational | Yes, within lead country only |
| | HIT AAA - High-intensity Interval Exercise Training prior to Abdominal Aortic Aneurysm Repair: A Feasibility Study (HIT AAA) | In Set-Up Pending NHS Permission | Interventional | No |
| | Hormonal Changes in Glycogen Storage Disease - Hormonal Changes in Glycogen Storage Disease | In Set-Up Pending NHS Permission | Observational | No |
| | Intravenous Iron in the Management of Anaemia in Palliative UGI Cancer - An pilot study to assess the efficacy of intravenous iron isomaltoside 1000 (Monofer®) in the management of anaemia associated with the palliative management of upper gastrointestinal adenocarcinoma | In Set-Up Pending NHS Permission | Interventional | No |
| | LIPS - A multi-centre (UK) double-blind randomised parallel group placebo controlled trial to evaluate the efficacy, safety, and tolerability of Intravenous Immunoglobulin (IVIg) 0.5g/kg plus standard treatment, versus matched placebo plus standard treatment in patients with longstanding Complex Regional Pain Syndrome | In Set-Up Pending NHS Permission | Interventional | No |
| | Magnetic Resonance Exercise Imaging in Congenital Heart Disease - Magnetic Resonance Exercise Imaging in Congenital Heart Disease | In Set-Up Pending NHS Permission | Observational | No |
| | Measuring oxygen consumption with lasers - An assessment of the practicality of in-line gas analysis for carbon dioxide, oxygen and water vapour in the settings of cardiopulmonary exercise testing, anaesthesia and intensive care | In Set-Up NHS Permission Received | Observational | No |
| | MED and Epidural Bupivacaine - Comparison of the ED95 dose of 0.075% and 0.1% bupivacaine for labour analgesia in primigravida | In Set-Up NHS Permission Received | Interventional | No |
| | METS Study - An International Multicentre Prospective Cohort Study of Cardiopulmonary Exercise Testing For Improving Preoperative Risk Stratification for Major Non-Cardiac Surgery | In Set-Up Pending NHS Permission | Observational | No |
| | Parental Home Monitoring and Assessment of Infants with Complex CHD - A Feasibility Study of Parental Home Monitoring and Early Assessment of Infants with Complex Congenital Heart Disease | In Set-Up Pending NHS Permission | Interventional | -unknown- |
| | PFAST: Patent Foramen Ovale and Stroke - PFAST: Patent Foramen Ovale and Stroke | In Set-Up NHS Permission Received | Observational | Yes, within and outside lead country |
| | Predicting Lung Function Decline in Adolescents with CF - Predicting Lung Function Decline in Adolescence: Which Children Need More Intervention? | In Set-Up Pending NHS Permission | Observational | No |
| | Predictors of Patient Uptake of Telehealth and Subsequent Abandonment - A longitudinal survey to determine predictors of chronic heart failure and chronic obstructive pulmonary disease patients' uptake of telehealth and subsequent abandonment | In Set-Up Pending NHS Permission | Observational | Yes, within lead country only |
| 67322816 | PREVENTT - A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery | In Set-Up Pending NHS Permission | Interventional | Yes, within lead country only |
| | Randomised Pilot Study Evaluating Two Group Therapies for TS - Group work for children with Tourette Syndrome (TS): A randomised pilot study to evaluate the efficacy of a tic-specific behavioural intervention versus psycho-education in improving tic severity, quality of life and neuropsychological functioning | In Set-Up Pending NHS Permission | Interventional | No |
| | Recovery Coaching in an Acute Hospital Setting - Evaluating a 'Recovery Coaching' Initiative in a Rehabilitation Ward for the Elderly | In Set-Up Pending NHS Permission | Interventional | -unknown- |
| | Renal Problems in Children with SCD - Management of Renal Complications in Children with Sickle Cell Disease | In Set-Up Pending NHS Permission | Observational | No |
| | Screening for Obstructive Sleep Apnoea in Children with Down Syndrome - Diagnostic test accuracy of a modified screening questionnaire and home pulse oximetry parameters in the diagnosis of obstructive sleep apnoea in children with Down syndrome | In Set-Up NHS Permission Received | Observational | No |
| | SIFT - Speed of Increasing milk Feeds Trial | In Set-Up NHS Permission Received | Interventional | Yes, within lead country only |
| | SOAP BOX - An observational study of tissue oxygen monitoring for detecting impending shock states in the critically ill and those undergoing high risk surgery | In Set-Up Pending NHS Permission | Observational | No |
| | Spreading a Health Message using Online Video - A Pilot Study - The Effectiveness of Spreading a Health Message using a Shareable Online Video Targeted at the Social Networks of Recently Diagnosed Individuals | In Set-Up Pending NHS Permission | Observational | No |
| | Study of Inherited Metabolic Diseases - Genetic and Biochemical Investigations of Children with Symptoms Suspicious for an Inherited Metabolic Disease | In Set-Up Pending NHS Permission | Observational | No |
| 94393315 | The CIRACT Trial - The CIRACT (Community In-reach Rehabilitation And Care Transition) Clinical and Cost Effectiveness study | In Set-Up NHS Permission Received | Interventional | No |
| | The Cleft Collective Cohort Studies - The Cleft Collective Cohort Studies - A large DNA backed prospective resource for the study of the genetic and environmental determinants of cleft lip and/or palate and the long term outcomes in children with cleft lip and/or palate | In Set-Up Pending NHS Permission | Observational | Yes, within lead country only |
| | The Cultural Representation of Older People - The Cultural Representation of Older People: Cultural Ageism and the Health and Social Care Sector | In Set-Up NHS Permission Received | Observational | No |
| | Use of an In Vitro Model to Study Novel Influenza Vaccines - Use of an In Vitro Model to Study Novel Influenza Vaccines | In Set-Up Pending NHS Permission | Observational | Yes, within lead country only |
| 55006384 | Warwick Spinal Immobiliser - Warwick Spinal Immobiliser - Development and Initial Trial of Prototype Spinal Immobilisation Device | In Set-Up Pending NHS Permission | Observational | No |